Physics-informed neural networks (PINNs) have opened exciting avenues for integrating mechanistic modeling with data-driven learning.
Nazanin Ahmadi, Brown University. From PINNs to PIKANs: Physics-Informed AI for Systems Biology and Pharmacology
Malvina Marku, Toulouse University Cancer Institute. Multi-scale computational modelling of tumour-immune interactions: from data-driven approaches to dynamical systems.
Understanding the regulatory mechanisms governing tumour-immune interactions is crucial for advancing targeted therapies in cancer.
Jacob Barhak, Lessons Learned from Modeling COVID-19: Steps to Take at the Start of the Next Pandemic
The COVID-19 pandemic spurred many computational modeling efforts. Many mistakes were made and many lessons were learned.
Julia C Arciero, Indiana University. Modeling novel immunoregulatory treatments for transplant patients
Successful organ transplantation is a lifesaving procedure, but it is met with serious risks including organ rejection, infection, and a compromised immune system.
Nazanin Ahmadi, Brown University. CMINNs: Compartment model informed neural networks—Unlocking drug dynamics
In the field of pharmacokinetics and pharmacodynamics (PKPD) modeling, which plays a pivotal role in the drug development process, traditional models frequently encounter difficulties in fully enca
Erin Zhao, Indiana University at Bloomington, Mathematical models of major arterial occlusion
Mathematical models of major arterial occlusion
Eran Agmon, University of Connecticut Health Compositional Systems Biology with Vivarium: Enabling Scalable, Hybrid Simulations of Cellular Systems
Eran Agmon, University of Connecticut Health
Markus Covert, Stanford University. "The E. coli Whole-Cell Modeling Project"
Francis Crick first called for a coordinated worldwide scientific effort to determine a “complete solution” of the bacterium Escherichia coli.
Ruirui Liu, U. of Nebraska Medical Center. Multiscale Digital Twins for Personalized Radiation Therapy
Recent advancements in radiation therapy have significantly improved treatment precision and patient outcomes.
Ramon Ortiz Catalan, UCSF: Multiscale Monte Carlo modeling for radiation therapy applications
Ramon Ortiz Catalan, University of California at San Francisco.
Multiscale Monte Carlo modeling for radiation therapy applications